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Hemoglobin A2

Hemoglobin A2, a normal variant of hemoglobin A, contains two alpha and two delta chains. It occurs in low levels in normal blood. It appears in excess in beta-thalassemia. Elevated HbA2 also occurs in hyperthyroidism and folate deficiency. They help in the formation of alpha-globin protein.

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How is the prognosis of a child with abnormal hemoglobin pattern?

Query: Hi doctor,My friend is going to adopt a 6 months old female child. Certain routine tests were performed on the child. I have attached the reports for your reference. The Hb electrophoresis for thalassemia screening is showing an abnormal hemoglobin pattern. The treating pediatrician is not sure abou...  Read Full »

Dr. Prakash. H. M.

Dr. Prakash. H. M.

Answer: Hi, Welcome to icliniq.com. Based on your query and attached report (attachment removed to protect patient identity), my opinion is as follows: Looking at the report of HbD trait (hemoglobin D), the prognosis is excellent. The child will be very rarely transfusion dependent and mostly asymptoma...  Read Full »

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