Are there any alternative treatments for MAC lung disease?

Question

Hello doctor,

I have Mycobacterium avium complex (MAC) lung disease that has not improved despite six months of antibiotic treatment. I am coughing up blood-tinged mucus every morning, and my fever persists. I have lost 22 pounds because eating worsens my coughing. My chest feels very tight and painful when I breathe. My pulmonologist is considering increasing my antibiotics from three to five, but I am already experiencing severe side effects. Are there any alternative treatments or options we can explore before adding more medications?

Please help.

Answer 1

Hello,

Welcome to icliniq.com.

I understand your concern.

Mycobacterium avium complex (MAC) lung infection has not improved after six months of antibiotic treatment. You are experiencing serious symptoms, including coughing up blood, significant weight loss, persistent fever, and chest pain when breathing. Although your pulmonologist plans to increase the number of antibiotics from three to five, you are already suffering from severe side effects.

Before adding more medications, consider these options:

Check for antibiotic resistance by repeating sputum tests to determine if the MAC bacteria have changed or if another infection is present.
A chest computed tomography (CT) scan to assess if the infection has spread or caused lung damage.
Inhaled antibiotics such as Amikacin (Arikayce) can deliver medication directly to the lungs with fewer systemic side effects compared to oral pills.
Airway clearance techniques, including saline nebulizers, chest physiotherapy, or specialized breathing devices, can help clear mucus from the lungs.
Nutritional support from a dietitian can help manage coughing triggered by eating and promote weight gain.
Seek a second opinion from a specialist or center experienced in treating difficult MAC lung disease cases.

I hope you are satisfied with my answer. For further queries, you can consult me at iCliniq.

Thank you.