Why can't I have my period without taking hormonal pills?

This Premium Q&A, reviewed and published, features a real conversation between an iCliniq user and a physician.

Patient's Query

Hello doctor,

I am 21 years old, 5 feet 5 inches tall, and weigh 119 pounds. I have not had my period for one year. During my consultation, the doctor said I have a small uterus and a lack of follicles. The doctor recommended that I take Diane 35 pills. But now, I cannot have my period without taking these pills.

What should I do?

Kindly help.

Hello,

Welcome to icliniq.com.

I understand your concern.

Your situation sounds difficult, and I understand how worrying it is to have no natural periods without taking pills. Diane 35 (Ethinylestradiol and Cyproterone Acetate) contains hormones called estrogen and progestin that make your body have withdrawal bleeding, which is like a fake period. However, this does not mean your ovaries and uterus are working normally on their own.

When you stop taking the pills, your body may still not produce the hormones needed for a natural cycle, so your periods do not come. If you have a small uterus and few follicles, possible causes include primary ovarian insufficiency, where your ovaries do not make enough estrogen; hypothalamic amenorrhea, caused by stress, low body weight, excessive exercise, or emotional strain; or other hormone problems like polycystic ovary syndrome, though this is less likely if you have no follicles.

The next step is to get a full hormone check-up, including tests for follicle-stimulating hormone, luteinizing hormone, estradiol, anti-Mullerian hormone, prolactin, and thyroid hormones, along with an ultrasound of your ovaries and uterus.

This will show if your brain is sending the right signals and if your ovaries are responding. It is important to see a reproductive hormone specialist or a gynecologist who understands hormone problems, as they can interpret your tests and suggest treatment. Also, ask about your bone health because without natural periods and estrogen, your bones may become weak, and you may need estrogen to protect them.

I hope you are satisfied with my answer.

For further queries, you can consult me at iCliniq.

Thank you.

Medically reviewed byiCliniq medical review team

Published At August 19, 2025
Reviewed AtAugust 22, 2025

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