Immunoglobulin E is synthesized by human beings' plasma cells and B-cells and plays a vital role in the body's defense mechanism. Of all the immunoglobulins, IgE is the least abundant in the human body. It is associated with hypersensitivity reactions and parasitic infections. IgE-mediated allergic reaction presents with allergic rhinitis, asthma, sinusitis, urticaria, and food allergies in response to certain potential triggering allergens.
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