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Innovative Pain Management Techniques in Critical Care

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Pain is a significant public health concern that poses a significant clinical, social, and financial challenge.

Medically reviewed by

Dr. Ankush Dhaniram Gupta

Published At February 27, 2024
Reviewed AtFebruary 27, 2024

Introduction

Emotional distress is a global public health concern that poses significant clinical, social, and financial challenges. Pain management should not be hindered by an intensive care unit (ICU) patient's incapacity to communicate pain due to mechanical breathing, concurrent sedative usage, or loss of consciousness. Among ICU patients, acute pain has become one of the main sources of stress. It has been noted that approximately 50 % of ICU patients experience moderate to severe pain severity. In ICU patients, a number of pharmacologic variables, including changed protein binding, altered volume status, changing pharmacokinetic and pharmacodynamic features with prolonged administration, and end-organ dysfunction, may enhance the likelihood of excessive or prolonged effects.

What Are the Specific Consequences of Improper Pain Management in the Intensive Care Unit?

The following are specific consequences of improper pain management in the intensive care unit (ICU):

  1. Self-removal of tubes and catheters.

  2. Aggression towards carers.

  3. Immune suppression related to pain.

  4. Prolonged mechanical ventilation.

  5. Increased ICU stay.

  6. Hypoxemia.

  7. Thromboembolic and pulmonary complications.

  8. Readmission for additional pain management.

  9. Agitation.

  10. Myocardial ischemia.

  11. Delirium.

  12. Chronic pain.

  13. Chronic mechanical ventilation and related issues like ventilator-associated pneumonia.

Do Patients Undergoing Various Surgical Procedures Require Different Forms of Analgesia?

For ICU patients on mechanical ventilation, a methodical approach to pain evaluation could serve as a standard for best practices in the ICU. Analgesic procedures have been thoroughly examined for their efficacy and results in treating acute pain, and they are widely used. The most recent practice guidelines were revised in February 2012 and accepted by the ASA as the "Practise Guidelines for Acute Pain Management in the Perioperative Setting." These guidelines are intended to lower the risk of unfavorable outcomes, preserve functional capacities, maintain physical and mental well-being, and enhance quality of life while facilitating the safety and efficacy of acute pain management in the perioperative period. Continued education and training are necessary to maintain one's abilities for the appropriate application of guidelines, especially as therapeutic techniques change.

Pain management techniques encompass the following modalities: Systemic opioids are used intermittently or continuously; central regional (i.e., neuraxial) opioid analgesia; multimodal techniques (administration of two or more drugs that act by different mechanisms to provide analgesia); and peripheral regional analgesic techniques, such as intercostal blocks, plexus blocks, and local anesthetic infiltration. ICU patients might benefit from medication dosage reduction techniques (also known as opioid-sparing effects). For those with cognitive impairments, behavioral modalities and approaches like PCA (patient-controlled analgesia) that rely on self-administration of analgesics are typically less appropriate.

Sedatives and analgesics are typically given to mechanical ventilation patients without further assessment. 90 % of patients in the ICU received opioids concurrently. However, according to a prospective multicenter observational survey, only 42 % of patients had their pain assessed on day two. According to the survey, measuring pain in patients using mechanical ventilation positively correlates with shorter ICU stays, shorter mechanical ventilation times, and lower doses of hypnotic drugs. Therefore, limiting the usage of hypnotic medicines and increasing concurrent rates of sedation assessment may be associated with pain assessment.

What Are the Strategies for Pain Management in Patients in the ICU?

An adequate, multimodal, and evidence-based pain management plan must be used in conjunction with an appropriate pain assessment. This multimodal approach should include pharmacologic and non-pharmacologic pain management techniques. An inclusive evaluation and management protocol is the suggested course of action, which guides suggested pain management techniques depending on pain ratings.

  • Management Without Drugs: Over the past few years, many non-pharmacologic techniques have gathered more and more support. The SCCM ICU liberation bundle 3 suggests massage therapy, cold therapy, sound and music therapy, and relaxation therapy as the four main non-pharmacologic approaches.

  • Non-pharmacologic Therapies: The aim is to treat pain perception's emotional, affective, and cognitive aspects (music and sounds, relaxation therapy) and the physical sensory pain pathways (massage therapy, cold therapy). One problem with critically sick patients is that they frequently find it difficult to express the feelings, perceptions, and experiences related to their pain. It has been demonstrated, nevertheless, that numerous of these techniques reduce behavioral pain ratings as well as self-reported pain scores.

  • Massage Therapy: ICU patients who receive massage therapy often have their hands, feet, and backs massaged. Massage using just the hands is also permissible, depending on the patient's clinical situation. At least twice in 24 hours, the ICU liberation bundle suggests giving yourself a low-pressure massage for at least 20 minutes. Massage is usually combined with lowering sensory input, such as turning down the lights, turning off the alarm, turning down the music, and giving the patient an eye mask or earplugs. Given the frequent disturbances in an ICU setting, this is frequently considered as an obstacle to the implementation of a massage routine. No feasibility studies on applying a massage protocol have been carried out.

  • Cold Therapy: Applying gauze-wrapped ice packs to procedural sites before the procedure has been described as cold therapy for pain management in intensive care unit patients. One can choose to use pharmacologic analgesia or not for this. This was done for 10 to 20 minutes before to the treatment until the skin reached 15º Centigrade, and it was linked to a 1-point decline on a 0 to 10 visual scale. The effects subsided after 15 minutes, according to a randomized study of individuals having their chest tubes removed.

  • Sound Therapy: Combined with music, music or sound therapy has been linked to modest reductions in pain levels in ICU patients. Since there is no physical risk to the patient from this intervention, it should be considered. The current research suggests waiting at least 20 to 30 minutes while considering the patient's preferences.

  • Relaxation Medicine Techniques: Used in relaxation therapy include guided imagery, breathing exercises, biofeedback, and self-hypnosis. In patients who are critically sick, guided imagery and breathing exercises are most commonly employed.

  • Pharmaceutical Administration: The cornerstone of care for patients in critical condition has been the use of pharmaceuticals to alleviate pain. Pharmacologic painkillers do not, however, come without side effects, which might result in undesired conditions, including delirium and opioid tolerance or withdrawal. Protocolized pain assessments should be used in conjunction with pharmacologic therapy, which should be applied in a graduated manner in response to pain ratings. SCCM guidelines advise using an opioid titration procedure based on pain scores for treating non-neuropathic pain as a first line of treatment. Additionally, they advocate for "analgosedation," a technique that manages pain before starting sedation therapy and only administers sedation when necessary. In certain patients, non-steroidal anti-inflammatory drugs (NSAIDs), Lidocaine infusions, and regional anesthesia are advised in addition to multimodal adjunct therapy such as Ketamine infusions, Acetaminophen, and Gabapentinoids.

Conclusion

In critically ill individuals, pain is poorly managed and has negative consequences. The critical care nurse must rely on the patient's sense of pain and how it manifests itself in their body's actions. Hemodynamic instability, respiratory assistance, varying degrees of consciousness, and the severity of the illness frequently hinder the expression and understanding of pain. An overview of the nursing literature on pain treatment in critically sick patients is included in this article. Alternative approaches are investigated, and current practices are examined. One novel strategy suggested as an addition to pharmacological treatments is therapeutic touch (TT). TT is a comprehensive, non-invasive method that encourages warmth, comfort, relaxation, and stress relief.

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Dr. Ankush Dhaniram Gupta
Dr. Ankush Dhaniram Gupta

Diabetology

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